The Isotope Separation On-Line (ISOL) technique evolved from chemical techniques used to separate radioactive isotopes off-line from irradiated "targets". The ISOL targets of today, used at e.g. ISOLDE, can be of many different types but the isotopes are always delivered at very low energies making the technique ideal for study of ground state properties and collections for other applications such as solid state physics and medical physics. The possibility of accelerating these low energy beams for nuclear structure studies, and in the long term future for neutrino physics, is now being explored at a first generation of radioactive beam facilities e.g. REX-ISOLDE. I will in this talk give an overview of the ISOL technique, the physics done at ISOLDE, the HIE-ISOLDE project proposal and the beta-beam concept for production of intense electron (anti-)neutrino beams from radioactive nuclei accelerated to high energies.
